Are zona pellucida genes involved in recurrent oocyte lysis observed during in vitro fertilization?
نویسندگان
چکیده
منابع مشابه
Oocyte zona pellucida dysmorphology is associated with diminished in-vitro fertilization success
BACKGROUND Although irregularities in human zona pellucida (ZP) morphology are well described, there is scant literature on the clinical significance of ZP dysmorphology. We, therefore, designed a retrospective cohort trial of ZP dysmorphology to assess the clinical significance of ZP dysmorphology and its affect on IVF outcome. Over the same time period a random sample of 77 cycles of 77 subje...
متن کاملEvaluation of Zona Pellucida Function for Sperm Penetration During In Vitro Fertilization in Pigs
In porcine oocytes, the function of the zona pellucida (ZP) with regard to sperm penetration or prevention of polyspermy is not well understood. In the present study, we investigated the effects of the ZP on sperm penetration during in vitro fertilization (IVF). We collected in vitro-matured oocytes with a first polar body (ZP+ oocytes). Some of them were freed from the ZP (ZP- oocytes) by two ...
متن کاملCorrelation between morphological abnormalities in the human oocyte zona pellucida, fertilization failure and embryonic development
Objective: The general patient condition, oocyte and embryo condition and clinical outcomes were studied in patients with a morphologically abnormal zona pellucida (ZP). Methods: The general embryo condition was compared between patients with a morphologically abnormal ZP or a normal ZP. The general embryo conditions in the first and subsequent cycles were compared in patients with a morphologi...
متن کاملMammalian fertilization: the egg's multifunctional zona pellucida.
The zona pellucida (ZP) is a specialized extracellular coat that surrounds the plasma membrane of mammalian eggs. Its presence is essential for successful completion of oogenesis, fertilization and preimplantation development. The ZP is composed of only a few glycoproteins which are organized into long crosslinked fibrils that constitute the extracellular coat. A hallmark of ZP glycoproteins is...
متن کاملCell adhesion and fertilization: steps in oocyte transport, sperm-zona pellucida interactions, and sperm-egg fusion.
Fertilization in mammals requires the successful completion of many steps, starting with the transport of gametes in the reproductive tract and ending with sperm-egg membrane fusion. In this minireview, we focus on three adhesion steps in this multistep process. The first is oocyte "pick-up," in which the degree of adhesion between the extracellular matrix of the cumulus cells and oviductal epi...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2013
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-013-0141-8